The secretome of senescent monocytes predicts age-related clinical outcomes in humans
Bradley Olinger, Reema Banarjee, Amit Dey, Dimitrios Tsitsipatis, Toshiko Tanaka, Anjana Ram, Thedoe Nyunt, Gulzar N. Daya, Zhongsheng Peng, Mansi Shrivastava, Linna Cui, Julián Candia, Eleanor M. Simonsick, Myriam Gorospe, Keenan A. Walker, Luigi Ferrucci, Nathan Basisty
Topics & Concepts
SenescencePhenotypeAgeingMonocyteMedicineCohortImmunologyBiologyBioinformaticsInternal medicineGeneticsGeneTelomeres, Telomerase, and SenescenceSingle-cell and spatial transcriptomicsNeutrophil, Myeloperoxidase and Oxidative Mechanisms