Litcius/Paper detail

Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection

Giovanni Luchetti, Justin L. Roncaioli, Roberto A. Chavez, Alexander F. Schubert, Eric M. Kofoed, Rohit Reja, Tommy K. Cheung, Yuxin Liang, Joshua D. Webster, Isabelle Lehoux, Elizabeth Skippington, Janina Reeder, Benjamin Haley, Man Tan, Christopher M. Rose, Kim Newton, Nobuhiko Kayagaki, Russell E. Vance, Vishva M. Dixit

2021Cell Host & Microbe186 citationsDOIOpen Access PDF

Topics & Concepts

BiologyPyroptosisUbiquitin ligaseMicrobiologyShigellaUbiquitinDegradation (telecommunications)DNA ligaseComputational biologyBacteriaBiochemistryGeneticsSalmonellaEnzymeApoptosisComputer scienceGeneProgrammed cell deathTelecommunicationsInflammasome and immune disordersAutoimmune and Inflammatory Disorders ResearchGout, Hyperuricemia, Uric Acid