Chitosan nanoparticles loaded with metformin and digoxin synergistically inhibit MCF-7 breast cancer cells through suppression of NOTCH-1 and HIF-1α gene expression
Hamed Dadashi, Milad Mashinchian, Alireza Karimian-Shaddel, Aria Mohabbat, Somayeh Vandghanooni, Morteza Eskandani, Rana Jahanban‐Esfahlan
Topics & Concepts
MCF-7MetforminDigoxinChitosanChemistryCancer researchGene expressionBreast cancerCancerGeneCell biologyEndocrinologyInternal medicinePharmacologyBiologyBiochemistryMedicineHuman breastInsulinHeart failureMicroRNA in disease regulationMetabolism, Diabetes, and CancerCancer, Hypoxia, and Metabolism