Litcius/Paper detail

A Manually Curated Gene Model Set for an Ascidian, Ciona robusta (Ciona intestinalis Type A)

Yutaka Satou, Miki Tokuoka, Izumi Oda‐Ishii, Sinichi Tokuhiro, Tasuku Ishida, Boqi Liu, Yuri Iwamura

2022ZOOLOGICAL SCIENCE51 citationsDOIOpen Access PDF

Abstract

Gene/transcript model sets predicted from decoded genome sequences are an important resource for a wide range of biological studies. Accuracy of gene models is therefore critical for deducing accurate conclusions. Computationally predicted models are sometimes inconsistent with experimental data from cDNA clones and RNA-sequencing. In an ascidian, Ciona robusta (Ciona intestinalis type A), a manually curated gene/transcript model set, which was constructed using an assembly in which 68% of decoded sequences were associated with chromosomes, had been used during the last decade. Recently a new genome assembly was published, in which over 95% of decoded sequences are associated with chromosomes. In the present study, we provide a high-quality version of the gene/transcript model set for the latest assembly. Because the Ciona genome has been used in a variety of studies such as developmental biological studies, evolutionary studies, and physiological studies, the current gene/transcript model set provides a fundamental biological resource.

Topics & Concepts

Ciona intestinalisCionaBiologyGenomeGeneComputational biologyGeneticsSet (abstract data type)Computer scienceProgramming languageMarine Ecology and Invasive SpeciesGenomics and Phylogenetic StudiesGenetic diversity and population structure