Metal–Organic Framework Derived Multicomponent Nanoagent as a Reactive Oxygen Species Amplifier for Enhanced Photodynamic Therapy
Dongdong Wang, Huihui Wu, Guangbao Yang, Cheng Qian, Long Gu, Hou Wang, Weiqiang Zhou, Jiawei Liu, Yinglong Wu, Xiaodong Zhang, Zhen Guo, Hongzhong Chen, Deblin Jana, Yanli Zhao
Abstract
. This study demonstrates that Glud-MFo-c acts as a ROS amplifier, providing a useful strategy to deeply understand the role of GSH in combating cancer.
Topics & Concepts
GlutathioneReactive oxygen speciesPhotodynamic therapyBiophysicsIntracellularMetalMaterials scienceCationic polymerizationCancer cellChemistryCombinatorial chemistryPhotochemistryBiochemistryOrganic chemistryPolymer chemistryBiologyCancerEnzymeGeneticsNanoplatforms for cancer theranosticsMetal-Organic Frameworks: Synthesis and ApplicationsPhotodynamic Therapy Research Studies