Engineering the precursor pool to modulate the production of pamamycins in the heterologous host S. albus J1074
Nils Gummerlich, Niko Manderscheid, Yuriy Rebets, Maksym Myronovskyi, Lars Gläser, Martin Kuhl, Christoph Wittmann, Andriy Luzhetskyy
Topics & Concepts
Streptomyces albusHeterologousBiologyHeterologous expressionStreptomycesBacteriaMutantGeneBiochemistryMetabolic engineeringBacillus subtilisMicrobiologyGeneticsRecombinant DNAMicrobial Natural Products and BiosynthesisGenomics and Phylogenetic StudiesRNA and protein synthesis mechanisms