Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease
Gopichand Gutti, Jennifer Leifeld, Kakarla Ramakrishna, Nilesh Gajanan Bajad, Ankit Ganeshpurkar, Ashok Kumar, Sairam Krishnamurthy, Christina Klein-Schmidt, Daniel Tapken, Michael Hollmann, Sushil Kumar Singh
Topics & Concepts
AdamantaneChemistryAcetylcholinesteraseIn vivoPharmacologyDrug discoveryBiochemistryEnzymeMedicineBiologyOrganic chemistryBiotechnologyCholinesterase and Neurodegenerative DiseasesPharmacological Receptor Mechanisms and EffectsComputational Drug Discovery Methods