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6PPD-quinone exposure induces neuronal mitochondrial dysfunction to exacerbate Lewy neurites formation induced by α-synuclein preformed fibrils seeding

Jiacheng Fang, Xiaoxiao Wang, Guodong Cao, Fuyue Wang, Yi Ru, Bolun Wang, Yanhao Zhang, Doudou Zhang, Jie Yan, Ji Xu, Jing Ji, Fenfen Ji, Yingyan Zhou, Lei Guo, Min Li, Wenlan Liu, Xiaodong Cai, Zongwei Cai, Zongwei Cai

2023Journal of Hazardous Materials105 citationsDOI

Topics & Concepts

NeurodegenerationNeuriteMitochondrionMetaboliteNeurotoxicityNeuroprotectionReactive oxygen speciesChemistryPINK1Oxidative stressOxidative phosphorylationRespiratory chainParkinson's diseaseCell biologyPharmacologyBiochemistryBiologyToxicityInternal medicineMitophagyMedicineApoptosisAutophagyDiseaseIn vitroOrganic chemistryParkinson's Disease Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments
6PPD-quinone exposure induces neuronal mitochondrial dysfunction to exacerbate Lewy neurites formation induced by α-synuclein preformed fibrils seeding | Litcius