Litcius/Paper detail

Propofol rescues voltage-dependent gating of HCN1 channel epilepsy mutants

Elizabeth D. Kim, Xiaoan Wu, Sangyun Lee, Gareth R. Tibbs, Kevin P. Cunningham, Eleonora Di Zanni, Marta E. Perez, Peter A. Goldstein, Alessio Accardi, H. Peter Larsson, Crina M. Nimigean

2024Nature19 citationsDOIOpen Access PDF

Topics & Concepts

PropofolGatingBiophysicsAllosteric regulationChemistryVoltage-gated ion channelElectrophysiologyIon channelNeurosciencePharmacologyBiochemistryBiologyEnzymeReceptorIon channel regulation and functionNeuroscience and Neuropharmacology ResearchElectrochemical Analysis and Applications