The proprotein convertase furin is a pro-oncogenic driver in KRAS and BRAF driven colorectal cancer
Zongsheng He, Lieven Thorrez, Géraldine Siegfried, Sandra Meulemans, Serge Évrard, Sabine Tejpar, Abdel‐Majid Khatib, John W.M. Creemers
Topics & Concepts
FurinKRASProprotein convertaseCancer researchMAPK/ERK pathwayBiologyColorectal cancerCarcinogenesisCancerSignal transductionCell biologyGeneticsEndocrinologyBiochemistryLipoproteinLDL receptorCholesterolEnzymeProtein Kinase Regulation and GTPase SignalingEndoplasmic Reticulum Stress and DiseaseProtein Tyrosine Phosphatases