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Genetic perturbation of AMP biosynthesis extends lifespan and restores metabolic health in a naturally short-lived vertebrate

Gwendoline Astre, Tehila Atlan, Uri Goshtchevsky, Adi Oron-Gottesman, Margarita Smirnov, Kobi Shapira, Ariel Velan, Joris Deelen, Tomer Levy, Erez Y. Levanon, Itamar Harel

2023Developmental Cell36 citationsDOI

Topics & Concepts

BiologyVertebrateBiosynthesisGeneticsEvolutionary biologyCell biologyZoologyGeneAdipose Tissue and MetabolismGenetics, Aging, and Longevity in Model OrganismsMitochondrial Function and Pathology
Genetic perturbation of AMP biosynthesis extends lifespan and restores metabolic health in a naturally short-lived vertebrate | Litcius