Niosomes as Biocompatible Scaffolds for the Multivalent Presentation of Tumor-Associated Antigens (TACAs) to the Immune System
Silvia Fallarini, Francesco Papi, Federico Licciardi, Francesca Natali, Grazia Lombardi, Francesca Maestrelli, Cristina Nativi
Abstract
). Unprecedentedly, structural differences, likely related to the carbohydrate portions, were observed for the two colloidal systems. Both niosomal systems are stable, nontoxic and endowed with promising immunogenic properties.
Topics & Concepts
NiosomeImmunogenicityChemistryAntigenImmune systemBiocompatible materialIn vitroMucinAntigen presentationVesicleNanotechnologyBiochemistryMembraneImmunologyBiomedical engineeringBiologyMedicineMaterials scienceCytotoxic T cellImmunotherapy and Immune ResponsesGlycosylation and Glycoproteins ResearchMonoclonal and Polyclonal Antibodies Research