Restoring glutamate homeostasis in the nucleus accumbens via endocannabinoid-mimetic drug prevents relapse to cocaine seeking behavior in rats
Lan-Yuan Zhang, Yue-Qing Zhou, Zhipeng Yu, Xiaoqin Zhang, Jie Shi, Haowei Shen
Topics & Concepts
Endocannabinoid systemMetabotropic glutamate receptorGlutamate receptorMetabotropic glutamate receptor 5Nucleus accumbensMetabotropic glutamate receptor 2PharmacologyAnandamideCannabinoid receptorCannabinoidMetabotropic glutamate receptor 1Metabotropic glutamate receptor 6Chemistry2-ArachidonoylglycerolNeuroscienceBiologyReceptorCentral nervous systemBiochemistryAgonistCannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior