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Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects

Genevieve H. L. Roberts, Raghavendran Partha, Brooke Rhead, Spencer C. Knight, Danny S. Park, Marie V. Coignet, Miao Zhang, Nathan Berkowitz, David A. Turrisini, Michael Gaddis, Shannon McCurdy, Miloš Pavlović, Luong Ruiz, Chodon Sass, AncestryDNA Science Team, Asher K. Haug Baltzell, Harendra Guturu, Ahna R. Girshick, Catherine A. Ball, Eurie L. Hong, Kristin A. Rand

2022Nature Genetics93 citationsDOIOpen Access PDF

Topics & Concepts

BiologyPhenotypeCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakGeneticsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Genetic associationGenome-wide association studyAssociation (psychology)Computational biologyGenotypeVirologySingle-nucleotide polymorphismGeneDiseaseOutbreakInfectious disease (medical specialty)PathologyEpistemologyMedicinePhilosophySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesPARP inhibition in cancer therapy
Expanded COVID-19 phenotype definitions reveal distinct patterns of genetic association and protective effects | Litcius