A Bridge Between in vitro and in vivo Studies in Neuroscience: Organotypic Brain Slice Cultures
Merve Alaylıoğlu, Erdinç Dursun, Selma Yılmazer, Duygu Gezen‐Ak
Abstract
-like environment since they maintain three-dimensional cytoarchitecture of the brain thus enable to study many cell types in one system and allow precise control of the microenvironment. In this review, we will focus on the history and key features of organotypic brain slice cultures as well as its preparation.
Topics & Concepts
NeuroscienceIn vitroBridge (graph theory)In vivoSlice preparationBiologyCentral nervous systemAnatomyBiochemistryBiotechnologyPluripotent Stem Cells ResearchNeuroscience and Neural Engineering3D Printing in Biomedical Research