Design and synthesis of novel (S)-Naproxen hydrazide-hydrazones as potent VEGFR-2 inhibitors and their evaluation in vitro/in vivo breast cancer models
M. İhsan Han, Pınar Atalay, Cansu Ümran Tunç, Gökhan Ünal, Serkan Dayan, Ömer Aydın, Ş. Güniz Küçükgüzel
Topics & Concepts
ChemistryNaproxenHydrazideHydrazoneIn vivoIn vitroMoietyStereochemistryCombinatorial chemistryPharmacologyBiochemistryOrganic chemistryAlternative medicineBiotechnologyBiologyPathologyMedicineEstrogen and related hormone effectsAngiogenesis and VEGF in CancerInflammatory mediators and NSAID effects