A practical approach for oligopeptide synthesis <i>via</i> synergistic photoredox, cobaloxime and organophosphorus triple catalysis
Junqi Su, Jia‐Nan Mo, Guofeng Zhang, Ziyu Jiang, Jiannan Zhao
Abstract
A catalytic oxidation–reduction condensation strategy for the synthesis of oligopeptides is reported. The triple catalytic system is compatible with all proteinogenic amino acids and applicable for multigram scale peptide synthesis.
Topics & Concepts
ChemistryOligopeptidePhotoredox catalysisCatalysisCombinatorial chemistryCondensationAmino acidPeptidePeptide synthesisOrganic chemistryBiochemistryPhotocatalysisPhysicsThermodynamicsChemical Synthesis and AnalysisClick Chemistry and ApplicationsRNA and protein synthesis mechanisms