Dual targeting of DR5 and VEGFR2 molecular pathways by multivalent fusion protein significantly suppresses tumor growth and angiogenesis
Alina A. Isakova, Artem A. Artykov, Е. А. Плотникова, Galina V. Trunova, Varvara А. Khokhlova, А. А. Панкратов, Margarita L. Shuvalova, D. V. Mazur, Н. В. Антипова, Mikhail I. Shakhparonov, Д. А. Долгих, М. П. Кирпичников, Marine E. Gasparian, Anne V. Yagolovich
Topics & Concepts
Cancer researchFusion proteinAngiogenesisImmunosurveillanceTumor microenvironmentChemistryReceptorAcetylationIn vitroBiologyTumor cellsBiochemistryRecombinant DNAGeneCell Adhesion Molecules ResearchImmunotherapy and Immune ResponsesGlioma Diagnosis and Treatment