Deracemization Enabled by Visible‐Light Photocatalysis
Qinglong Shi, Juntao Ye
Abstract
Deracemization is an ideal but challenging strategy for the conversion of a racemic mixture into a single enantiomer. Recent studies have demonstrated that visible-light photocatalysis could be utilized to promote selective deracemization of axially chiral allenes as well as cyclopropylquinolones and cyclic ureas with central chirality either through energy transfer or through a sequence of electron, proton, and hydrogen-atom transfer.
Topics & Concepts
PhotocatalysisChirality (physics)Hydrogen atomEnantiomerPhotochemistryMaterials scienceElectron transferEnergy transferVisible spectrumProtonNanotechnologyChemistryCombinatorial chemistryCatalysisStereochemistryChemical physicsPhysicsOrganic chemistryOptoelectronicsChiral symmetryQuarkAlkylQuantum mechanicsNambu–Jona-Lasinio modelRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSynthesis and Catalytic Reactions