Zinc binding loop mutations of hSOD1 promote amyloid fibrils under physiological conditions: Implications for initiation of amyotrophic lateral sclerosis
Payam Baziyar, Bagher Seyedalipour, Saman Hosseinkhani
Topics & Concepts
MutantBiophysicsFibrilAmyloid (mycology)ChemistryProtein aggregationAmyotrophic lateral sclerosisToxicityMutationCell biologyBiochemistryBiologyPathologyGeneMedicineOrganic chemistryInorganic chemistryDiseaseAmyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding