Colorectal cancer chemoprevention: is aspirin still in the game?
Adrien Grancher, Pierre Michel, Frédéric Di Fiore, David Sefrioui
Abstract
-mutated tumors. This review summarizes current knowledge on the pathophysiological mechanisms of aspirin chemoprevention, discusses the primary clinical results on CRC prevention and highlights the potential biomarkers identified to predict aspirin efficacy.
Topics & Concepts
AspirinMedicineColorectal cancerPrimary preventionIncidence (geometry)Internal medicineOncologyCancerDiseasePhysicsOpticsInflammatory mediators and NSAID effectsCancer, Lipids, and MetabolismCancer, Stress, Anesthesia, and Immune Response