Fabricating nanoparticles co-loaded with survivin siRNA and Pt(IV) prodrug for the treatment of platinum-resistant lung cancer
Shuting Ma, Xiaowen Li, Meixin Ran, Muse Ji, Jingxin Gou, Tian Yin, Haibing He, Yanjiao Wang, Yu Zhang, Xing Tang
Topics & Concepts
SurvivinCisplatinCancer cellApoptosisPolyglutamic acidNanocarriersChemistryCancer researchProdrugA549 cellCytotoxicityPharmacologyCancerIn vitroChemotherapyDrugBiochemistryMedicineInternal medicineAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery