Isoorientin attenuates doxorubicin-induced cardiac injury via the activation of MAPK, Akt, and Caspase-dependent signaling pathways
Shaoguang Li, Huilin Liu, Zhan Lin, Zhijun Li, Yan Chen, Bing Chen, Liying Huang, Xinhua Lin, Hong Yao
Topics & Concepts
DoxorubicinPharmacologyHeart failureApoptosisProtein kinase BMedicineMyocardial infarctionReactive oxygen speciesCancer researchChemotherapyChemistryInternal medicineBiochemistryChemotherapy-induced cardiotoxicity and mitigationCell death mechanisms and regulationCardiac Fibrosis and Remodeling