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Halogen-bond-assisted radical activation of glycosyl donors enables mild and stereoconvergent 1,2-cis-glycosylation

Chen Zhang, Hao Zuo, Ga Young Lee, Yike Zou, Qiu-Di Dang, K. N. Houk, Dawen Niu

2022Nature Chemistry152 citationsDOI

Topics & Concepts

ChemistryGlycosylGlycosylationNucleophileStereoselectivityGlycosidic bondElectrophileLewis acids and basesCombinatorial chemistryGlycosyl donorGlycalHalogenPhotoredox catalysisStereochemistryCatalysisOrganic chemistryPhotocatalysisAlkylBiochemistryEnzymeCarbohydrate Chemistry and SynthesisLegume Nitrogen Fixing SymbiosisSulfur-Based Synthesis Techniques
Halogen-bond-assisted radical activation of glycosyl donors enables mild and stereoconvergent 1,2-cis-glycosylation | Litcius