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Ezrin inhibition alleviates oxidative stress and pyroptosis via regulating TRPML1-calcineurin axis mediated enhancement of autophagy in spinal cord injury

Junsheng Lou, Mengran Jin, Conghui Zhou, Yunpeng Fan, Libin Ni, Yiting Mao, Honghao Shen, Jiafeng Li, Haojie Zhang, Chunyan Fu, Xingjia Mao, Yingying Chen, Jinjie Zhong, Kailiang Zhou, Linlin Wang, Junsong Wu, Junsong Wu

2023Free Radical Biology and Medicine14 citationsDOI

Topics & Concepts

PyroptosisAutophagyOxidative stressCell biologySpinal cord injuryEzrinPI3K/AKT/mTOR pathwayProgrammed cell deathSignal transductionChemistryCancer researchNeuroscienceSpinal cordMedicineApoptosisBiologyCellBiochemistryCytoskeletonCalcium signaling and nucleotide metabolismAutophagy in Disease and TherapyAdvanced battery technologies research
Ezrin inhibition alleviates oxidative stress and pyroptosis via regulating TRPML1-calcineurin axis mediated enhancement of autophagy in spinal cord injury | Litcius