Phosphorylated tau exhibits antimicrobial activity capable of neutralizing herpes simplex virus 1 infectivity in human neurons
William A. Eimer, Alex S. Rodriguez, Michael T. DeFao, Simon Ehricke, Joseph Park, Deepak Kumar Vijaya Kumar, Nanda Kumar N. Shanmugam, Sanjana Singh, Tara Sawhney, Robert D. Moir, Rudolph E. Tanzi
Topics & Concepts
Innate immune systemHerpes simplex virusInfectivityAntimicrobialPhosphorylationImmune systemMicrogliaBiologyTauopathyVirologyTau proteinLytic cycleVirusCell biologySenile plaquesAmyloid (mycology)ChemistryAmyloid betaAntimicrobial peptidesCytoskeletonMicrotubulePeptideBeta defensinNeuropathologyNeuroscienceMicrobiologyHuman brainAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsCellular transport and secretion