Litcius/Paper detail

Controversy and Progress in Alzheimer’s Disease — FDA Approval of Aducanumab

Gil D. Rabinovici

2021New England Journal of Medicine151 citationsDOI

Abstract

Interview with Dr. Gil Rabinovici on the FDA’s controversial approval of a new treatment for Alzheimer’s disease. (16:39)Download The FDA’s accelerated approval of aducanumab represents a landmark moment, though the drug’s road to the clinic has been rocky and contentious. The hope is that despite its limitations, this first-in-class drug will open the door to more efficacious therapies.

Topics & Concepts

MedicineDrug approvalDiseaseDrugFamily medicinePsychiatryPathologyCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsNuclear Receptors and Signaling