10-Gingerol, a natural AMPK agonist, suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation
Bo Deng, Xiaoli Jiang, You‐cai Xu, Si Chen, Min Cai, Suihui Deng, Wenjun Ding, Honglin Xu, Shuangwei Zhang, Zhang‐Bin Tan, Ruixue Chen, Bin Liu, Jingzhi Zhang
Abstract
: These data showed that 10-G might inhibit neointimal hyperplasia and suppress VSMC proliferation by the activation of AMPK as a natural AMPK agonist.
Topics & Concepts
Neointimal hyperplasiaAMPKVascular smooth muscleCell growthChemistryCellCell biologyProtein kinase AEndocrinologyInternal medicinePhosphorylationBiologyMedicineBiochemistryRestenosisStentSmooth muscleGinger and Zingiberaceae researchKruppel-like factors research