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Organ-specific isoform selection of fatty acid–binding proteins in tissue-resident lymphocytes

Hannah Frizzell, Raíssa Fonseca, Susan N. Christo, Maximilien Evrard, Sebastián Cruz-Gómez, Nágela Ghabdan Zanluqui, Bianca von Scheidt, David Freestone, Simone L. Park, Hamish E. G. McWilliam, Jóse A. Villadangos, Francis R. Carbone, Laura K. Mackay

2020Science Immunology129 citationsDOIOpen Access PDF

Abstract

Tissue-resident cells exhibit tissue-specific overlays to the T RM cell residency program that includes flexible FABP isoform selection tailored to the tissue of lodgment.

Topics & Concepts

Gene isoformSelection (genetic algorithm)BiologyCell biologyBiochemistryGeneComputer scienceArtificial intelligenceImmune Cell Function and InteractionImmune Response and InflammationT-cell and B-cell Immunology
Organ-specific isoform selection of fatty acid–binding proteins in tissue-resident lymphocytes | Litcius