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Synthesis, properties and chemical modification of a persistent triisopropylsilylethynyl substituted tri(9-anthryl)methyl radical

Tomohiko Nishiuchi, Daisuke Ishii, Seito Aibara, Hiroyasu Sato, Takashi Kubo

2022Chemical Communications20 citationsDOIOpen Access PDF

Abstract

In studies aimed at developing new organic spin materials, we prepared a triisopropylsilylethynyl substituted tri(9-anthryl)methyl (TAntM) radical. The TIPS-ethynyl group in this radical effectively suppresses its reactivity, resulting in extremely high stability in air for at least one month. Chemical modification of the radical using [4+2] Diels-Alder reaction proceeds even at room temperature. Because harsh conditions and metal-catalyzed reactions are not required, this post-modification strategy should be highly versatile for use in constructing unique spin-labelled molecules.

Topics & Concepts

ChemistryReactivity (psychology)Chemical modificationReactive intermediateRadicalMoleculeChemical synthesisPhotochemistryOrganic chemistryCombinatorial chemistryCatalysisPolymer chemistryIn vitroBiochemistryPathologyAlternative medicineMedicineOrganoboron and organosilicon chemistryRadical Photochemical ReactionsLuminescence and Fluorescent Materials
Synthesis, properties and chemical modification of a persistent triisopropylsilylethynyl substituted tri(9-anthryl)methyl radical | Litcius