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Efficacy of subsequent chemotherapy for patients with BRCA1/2-mutated recurrent epithelial ovarian cancer progressing on olaparib versus placebo maintenance: post-hoc analyses of the SOLO2/ENGOT Ov-21 trial

Jean‐Sébastien Frenel, J.W. Kim, Nanda Aryal, Rebecca Asher, Dominique Berton, Laura Vidal, Patricia Pautier, Jonathan A. Ledermann, Richard T. Penson, Amit M. Oza, Jacob Korach, Tomasz Huzarski, Sandro Pignata, Nicoletta Colombo, Tjoung-Won Park-Simon, Kenji Tamura, Gabe S. Sonke, Alison Freimund, Chee Khoon Lee, Éric Pujade-Lauraine

2022Annals of Oncology155 citationsDOIOpen Access PDF

Topics & Concepts

OlaparibMedicineHazard ratioInternal medicinePlaceboChemotherapyOncologyOvarian cancerPopulationCohortSurgeryCancerConfidence intervalPathologyPolymerasePoly ADP ribose polymeraseGeneChemistryBiochemistryAlternative medicineEnvironmental healthPARP inhibition in cancer therapyOvarian cancer diagnosis and treatmentBRCA gene mutations in cancer
Efficacy of subsequent chemotherapy for patients with BRCA1/2-mutated recurrent epithelial ovarian cancer progressing on olaparib versus placebo maintenance: post-hoc analyses of the SOLO2/ENGOT Ov-21 trial | Litcius