Cancer-Associated Fibroblast-Derived IL-8 Upregulates PD-L1 Expression in Gastric Cancer Through the NF-κB Pathway
Meiyue Lou, Masaaki Iwatsuki, Xiyu Wu, W Zhang, Chihiro Matsumoto, Hideo Baba
Topics & Concepts
Cancer researchCytotoxicityCancer cellCytotoxic T cellTumor microenvironmentCD8Cell cultureMolecular biologyDownregulation and upregulationp38 mitogen-activated protein kinasesSmall interfering RNAImmune systemChemistrySignal transductionBiologyCell biologyCancerTransfectionMedicineIn vitroImmunologyMAPK/ERK pathwayInternal medicineBiochemistryGeneGeneticsCancer Immunotherapy and BiomarkersCancer Cells and MetastasisImmune cells in cancer