Litcius/Paper detail

GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity

Sabine Heitzeneder, Kristopher R. Bosse, Zhongyu Zhu, Doncho V. Zhelev, Robbie G. Majzner, Molly Radosevich, Shaurya Dhingra, Elena Sotillo, Samantha N. Buongervino, Guillem Pascual‐Pasto, Emily Garrigan, Peng Xu, Jing Huang, Benjamin Salzer, Alberto Delaidelli, Swetha Raman, Hong Cui, Benjamin Martinez, Scott J. Bornheimer, Bita Sahaf, Anya S. Alag, Irfete S. Fetahu, Martin Hasselblatt, Kevin R. Parker, Hima Anbunathan, Jennifer Hwang, Min Huang, Kathleen M. Sakamoto, Norman J. Lacayo, Dorota D. Klysz, Johanna Theruvath, José G. Vilches-Moure, Ansuman T. Satpathy, Howard Y. Chang, Manfred Lehner, Sabine Taschner‐Mandl, Jean-Phillipe Julien, Poul H. Sorensen, Dimiter S. Dimitrov, John M. Maris, Crystal L. Mackall

2021Cancer Cell164 citationsDOIOpen Access PDF

Topics & Concepts

Chimeric antigen receptorNeuroblastomaAntigenCancer researchBiologyImmune systemCell cultureCell biologyImmunologyT cellGeneticsCAR-T cell therapy researchNeuroblastoma Research and TreatmentsVirus-based gene therapy research