Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells
Kshitiz Gupta, Junaid Afzal, Yasir Suhail, Hao Chang, Maimon E. Hubbi, Archer Hamidzadeh, Ruchi Goyal, Yamin Liu, Peng Sun, Stefania Nicoli, Chi V. Dang, Andre Levchenko
Topics & Concepts
Cell biologyAutophagyCancer cellHypoxia (environmental)BiologyDownregulation and upregulationIntracellularExtracellularCell cultureCellCell growthCancer researchChemistryGeneCancerApoptosisBiochemistryOxygenGeneticsOrganic chemistryCancer, Hypoxia, and MetabolismAutophagy in Disease and TherapyMitochondrial Function and Pathology