Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways
Jiale Cai, Jiayin Liang, Yutong Zhang, Lin Shen, Huiting Lin, Tao Hu, Sikai Zhan, Meixia Xie, Shengwang Liang, Minghua Xian, Shumei Wang
Topics & Concepts
JUNBMicrogliaPharmacologyNeuroinflammationInflammationOxidative stressReperfusion injuryApoptosisProinflammatory cytokinePI3K/AKT/mTOR pathwayChemistryNF-κBMedicineNeuroprotectionIschemiaImmunologyBiochemistryInternal medicineTranscription factorGeneNeuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and TreatmentsTraditional Chinese Medicine Analysis