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A mating mechanism to generate diversity for the Darwinian selection of DNA-encoded synthetic molecules

Balayeshwanth R. Vummidi, Lluc Farrera‐Soler, Jean‐Pierre Daguer, Millicent Dockerill, Sofía Barluenga, Nicolas Winssinger

2021Nature Chemistry48 citationsDOI

Topics & Concepts

DNA shufflingShufflingChemistryComputational biologySelection (genetic algorithm)StreptavidinDNADirected evolutionGenomic libraryCombinatorial chemistryComputer scienceMutantBase sequenceBiologyArtificial intelligenceGeneBiochemistryBiotinProgramming languageMonoclonal and Polyclonal Antibodies ResearchChemical Synthesis and AnalysisBiochemical and Structural Characterization
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