A mitochondrial SCF‐FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease
Yu Cao, Jing Zheng, Huayun Wan, Yuqiu Sun, Song Fu, Shanshan Liu, Baiyu He, Gaihong Cai, Yang Cao, Huanwei Huang, Qi Li, Yan Ma, She Chen, Fengchao Wang, Hui Jiang
Topics & Concepts
MitophagyUbiquitin ligaseBiologyMitochondrionCell biologyUbiquitinAutophagyParkinKnockout mouseBiochemistryReceptorGeneApoptosisDiseaseMedicineParkinson's diseasePathologyAutophagy in Disease and TherapyUbiquitin and proteasome pathwaysEndoplasmic Reticulum Stress and Disease