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Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis

Yong Hwan Park, Elaine F. Remmers, Wonyong Lee, Amanda K. Ombrello, Lawton K. Chung, Shilei Zhao, Deborah L. Stone, Maya I. Ivanov, Nicole A. Loeven, Karyl S. Barron, Patrycja Hoffmann, Michele Nehrebecky, Yeliz Z. Akkaya‐Ulum, Erdal Sağ, Banu Balcı‐Peynircioğlu, Ivona Aksentijevich, Ahmet Gül, Charles N. Rotimi, Hua Chen, James B. Bliska, Seza Özen, Daniel L. Kastner, Daniel Shriner, Jae Jin Chae

2020Nature Immunology152 citationsDOIOpen Access PDF

Topics & Concepts

Pyrin domainFamilial Mediterranean feverMEFVBiologyYersinia pestisGeneticsInflammasomeMutationMutantMicrobiologyVirulenceImmunologyGeneMedicineGene mutationDiseaseReceptorPathologyInflammasome and immune disordersinterferon and immune responsesImmune Response and Inflammation
Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis | Litcius