Antimicrobial Susceptibility Survey of Invasive Haemophilus influenzae in the United States in 2016
Caelin Cubeñas-Potts, Lorraine D. Rodriguez‐Rivera, Adam C. Retchless, Sean Buono, Alexander T. Chen, Henju Marjuki, Amy Blain, Xin Wang
Abstract
Antibiotics play an important role for the treatment and prevention of invasive Haemophilus influenzae disease. Antimicrobial resistance survey of invasive H. influenzae isolates collected in 2016 showed that the US H. influenzae population remained susceptible to clinically relevant antibiotics, except for ampicillin. Detection of approximately a quarter ampicillin-resistant and β-lactamase containing strains demonstrates that resistance mechanisms can be acquired and sustained within the H. influenzae population, highlighting the continued importance of antimicrobial resistance surveillance for H. influenzae to monitor susceptibility trends and mechanisms of resistance.