Litcius/Paper detail

Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities

Jian Song, Yong-Feng Guan, Wen‐Bo Liu, Chun-Hong Song, Xin-Yi Tian, Ting Zhu, Xiang-Jing Fu, Ying-Qiu Qi, Sai‐Yang Zhang

2022European Journal of Medicinal Chemistry46 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryMAPK/ERK pathwayTubulinCancer cellKinaseMicrotubule polymerizationCancerCell growthApoptosisCoumarinCell cycleIC50Cell culturePharmacologyMicrotubuleBiochemistryCancer researchIn vitroCell biologyBiologyInternal medicineMedicineGeneticsOrganic chemistrySynthesis and biological activityQuinazolinone synthesis and applicationsFungal Plant Pathogen Control