Colon-specific delivery of methotrexate using hyaluronic acid modified pH-responsive nanocarrier for the therapy of colitis in mice
Yingni Lv, Mengjiao Ren, Min Yao, Jiafeng Zou, Siqi Fang, Yanbing Wang, Minbo Lan, Yuzheng Zhao, Feng Gao
Topics & Concepts
Hyaluronic acidNanocarriersIn vivoColitisMethotrexatePharmacologyInflammatory bowel diseasePLGAChemistryMyeloperoxidaseDrug deliveryIn vitroInflammationDrugMedicineImmunologyBiochemistryPathologyBiologyOrganic chemistryDiseaseBiotechnologyAnatomyInflammatory Bowel DiseaseMicroscopic ColitisAutoimmune and Inflammatory Disorders