Allostery governs Cdk2 activation and differential recognition of CDK inhibitors
Abir Majumdar, David J. Burban, Joseph M. Muretta, Andrew R. Thompson, Tiffany A. Engel, Damien M. Rasmussen, Manu Veliparambil Subrahmanian, Gianluigi Veglia, David D. Thomas, Nicholas M. Levinson
Topics & Concepts
Cyclin-dependent kinaseAllosteric regulationCyclin-dependent kinase 2Cell biologyCDK inhibitorCyclin ABiologyAllosteric enzymeKinaseBiophysicsBiochemistryChemistryCell cycleProtein kinase AEnzymeCellCancer-related Molecular PathwaysMicrotubule and mitosis dynamicsGenomics and Chromatin Dynamics