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Super-resolution observation of lysosomal dynamics with fluorescent gold nanoparticles

Kangqiang Qiu, Yang Du, Jiyan Liu, Jun‐Lin Guan, Hui Chao, Jiajie Diao

2020Theranostics67 citationsDOIOpen Access PDF

Abstract

was successfully used as a lysosomal probe for the super-resolution observation in living cells and found to overcome the limitations of commercial LysoTrackers. Our results thus confirm that nanoparticles can be useful tools for subcellular super-resolution imaging and highlight new avenues for using nanoparticles in biology.

Topics & Concepts

FluorescenceDynamics (music)NanoparticleColloidal goldNanotechnologyBiophysicsChemistryMaterials scienceBiologyPhysicsOpticsAcousticsAdvanced Fluorescence Microscopy TechniquesCell Image Analysis TechniquesRetinal Development and Disorders
Super-resolution observation of lysosomal dynamics with fluorescent gold nanoparticles | Litcius