Single-nucleotide-level mapping of DNA regulatory elements that control fetal hemoglobin expression
Li Cheng, Yichao Li, Qian Qi, Peng Xu, Ruopeng Feng, Lance E. Palmer, Jingjing Chen, Ruiqiong Wu, Tiffany Yee, Jingjing Zhang, Yu Yao, Akshay Sharma, Ross C. Hardison, Mitchell J. Weiss, Yong Cheng
Topics & Concepts
BiologyFetal hemoglobinRepressorGeneticsRegulatory sequenceChromosome conformation captureGeneRegulation of gene expressionGene expressionFetusEnhancerPregnancyHemoglobinopathies and Related DisordersEpigenetics and DNA MethylationRNA modifications and cancer