Plasmon enhanced catalysis-driven nanomotors with autonomous navigation for deep cancer imaging and enhanced radiotherapy
Luntao Liu, Qingqing Li, Lanlan Chen, Lihong Song, Xue‐Qiang Zhang, Hongqi Huo, Zhixin You, Ying Wu, Zongsheng Wu, Jiamin Ye, Qinrui Fu, Lichao Su, Xuan Zhang, Huanghao Yang, Jibin Song
Abstract
NIR-catalysis on one side of the Au nanorod, which prevents them from returning to circulation and effectively improves the sample accumulation in the tumor. Additionally, a high radiation dose deposition in the form of more hydroxyl radical generation and glutathione depletion is authenticated. Thus, synergistically enhanced radiotherapeutic efficacy is achieved in both a subcutaneous tumor model and an orthotopic model.
Topics & Concepts
PlasmonNanotechnologyCatalysisChemistryMaterials scienceOptoelectronicsBiochemistryMicro and Nano RoboticsMolecular Communication and NanonetworksNanoplatforms for cancer theranostics