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Design, synthesis, biological evaluation, in silico ADME prediction and molecular docking of pyrazole-benzamides as multitargeting protien kinase inhibitors

Nada A Khaled, Nesreen S. Ahmed, Ahmed Z. Abdelazem, Neama A. Mohamed, Ahmed F. El‐Sayed, Sayed A. Ahmed

2023Journal of Molecular Structure25 citationsDOI

Topics & Concepts

ADMEChemistryPyrazolePharmacologyDoxorubicinIn silicoIC50Docking (animal)In vivoPharmacokineticsPaclitaxelIn vitroStereochemistryBiochemistryCancerChemotherapyInternal medicineNursingGeneBiotechnologyMedicineBiologyQuinazolinone synthesis and applicationsSynthesis and biological activityCancer Mechanisms and Therapy
Design, synthesis, biological evaluation, in silico ADME prediction and molecular docking of pyrazole-benzamides as multitargeting protien kinase inhibitors | Litcius