A case of varicella zoster virus meningitis following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient
Taketomo Maruki, Masahiro Ishikane, Tetsuya Suzuki, Mugen Ujiie, Harutaka Katano, Norio Ohmagari
Abstract
We report a case of varicella zoster virus (VZV) meningitis following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient. A final diagnosis was made based on identification of VZV via positive polymerase chain reaction of cerebrospinal fluid along with characteristic symptoms such as fever, headache, and stiff neck. This phenomenon has been reported elsewhere; this is the 13th such case reported worldwide and the 7th case in immunocompetent patients, indicating the need for careful monitoring after COVID-19 vaccines.
Topics & Concepts
MedicineVaccinationVirologyVaricella zoster virusCoronavirus disease 2019 (COVID-19)MeningitisVirusCerebrospinal fluidPediatricsPathologyDiseaseInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchHerpesvirus Infections and TreatmentsPeripheral Neuropathies and Disorders