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The Structures and Functions of Parvovirus Capsids and Missing Pieces: the Viral DNA and Its Packaging, Asymmetrical Features, Nonprotein Components, and Receptor or Antibody Binding and Interactions

Robert A. López-Astacio, Oluwafemi F. Adu, Hyunwook Lee, Susan Hafenstein, Colin R. Parrish

2023Journal of Virology21 citationsDOIOpen Access PDF

Abstract

share a capsid architecture, and while many functions are likely similar, others may differ in detail. Many of those parvoviruses have not been experimentally examined in detail (or at all in some cases), so we, therefore, focus this minireview on the widely studied protoparvoviruses, as well as the most thoroughly investigated examples of adeno-associated viruses.

Topics & Concepts

CapsidParvovirusBiologyMinute virus of miceCanine parvovirusParvoviridaeVirologyDNAVirusMolecular biologyGeneticsVirus-based gene therapy researchParvovirus B19 Infection StudiesAnimal Virus Infections Studies