A fragment-based structural analysis of MMP-2 inhibitors in search of meaningful structural fragments
Suvankar Banerjee, Sk. Abdul Amin, Tarun Jha
Topics & Concepts
Matrix metalloproteinaseProteasesChemistryComputational biologyMatrix metalloproteinase inhibitorExtracellular matrixDrug discoveryBiochemistryActive siteStereochemistryHydrogen bondIn silicoEnzymeCombinatorial chemistryCancer researchMoleculeBiologyGeneOrganic chemistryProtease and Inhibitor MechanismsPeptidase Inhibition and AnalysisEnzyme Production and Characterization