Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors
Beining Jin, Naveen Thakur, Anuradha V. Wijesekara, Matthew T. Eddy
Topics & Concepts
G protein-coupled receptorAllosteric regulationReceptorNuclear magnetic resonance spectroscopyIntracellularExtracellularBiophysicsBiologySignal transductionComputational biologyChemistryCell biologyBiochemistryStereochemistryReceptor Mechanisms and SignalingMass Spectrometry Techniques and ApplicationsIon channel regulation and function